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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ba3c4be2c7109131def6a0e94b8150dc3fd258a991d743cb0f727922fc4277' 
  AND token = 'n6jkAy890X+hst+cCWDA5UgTl8FL6guzQn2z8jgE1SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}