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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221e95b9ef2b04ee550439136181b778c922aec24b18f67bb9a82ac3c341e083' 
  AND token = 'Uxa9JeMnaKRbSTXSVO6LXkhhJKACnHw8ZcuNj/4mqao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}