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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac488f3104056bc8ae06ffca9068fe7378cc3c4a51adce6b7591d2b935a07dfd' 
  AND token = 'jXFFtgvQwqevAdp9oggngCW8SiFD4sN+T60VY5Lg3Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}