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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c35a1188d42508859aea1ffa85eb9cba6b039926511c6bf3cbd171a8e2cf4af' 
  AND token = 'eRZZoForIl9YpVVI4UmcOPN7KfAKroumtK/fpoccWpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}