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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb5c21a60b52a42a5f1a93386113064599058b0371b72b89940081b89766cd6' 
  AND token = 'VbKM6cn8/k4ncZQ1YGd6QbX6GKCJ/45pcpc2Sf4uHwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}