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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05fb0fcd4efd9e1b1cc579a490e04a657ee629bc290cf0ecc975e55c47801095' 
  AND token = 'A5TB8QoRtmtT6FbG3To0k2Fx6H5q1owZDzZZr08ZbHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}