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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4499fa8e7d64478625862b457a9e38a6316d4098b57474e9dd1136d6fdbab0c9' 
  AND token = '165vhAfMIlKyY9rNT3OgxUYYuXcedzgEovivicBYktg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}