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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6b9a2b10336684516c21b05cfee21f3ef70b894516a0598c4d975b20f3667b' 
  AND token = 'isF/2+V/KIk9mArjXCPtpUf9xHd1YRmqC0eSLZ09TCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}