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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dbde3a882ad8e0e434cf0040b3ced9c2937202827066c1525728803d729b5e' 
  AND token = '2eq8MloyXPHerG2DfAKNiWkNo4eRudwfHuiOWyHubMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}