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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4ab2e4ff93f2dd85efa9c084cc3a42cf902f7855f156f93cad955042105abb' 
  AND token = 'uUVgeOyK+QrxOgAmIum1C52JYsaY7KYMXPNVRGPyvC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}