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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de845e9349a806a5575a5473b8f55763e5c2c7b46455781a2871e1e3fd894078' 
  AND token = '/ztAAZc/gSvkpg8+fwHV6axXCHA7J/Y/yBMfn2zt76M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}