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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49bc98000b0b6a991e3583a7aa78488408ae768d74b1b5a7665501c6447be18' 
  AND token = 'T/esCdPf94J1vsQ4Bz9hEtZPnw83/SQ9JhIjfP6y4eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}