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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5e45395967b138eba862734189e88bd1b15bf0098376f663250a602b1e034e' 
  AND token = 'k1ow69NwIUz0OQvmFwK7ON4eKvmCXwto6/a5knwODVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}