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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f42ac05c3149c82da7bb4081e7179f486f2cdf311c453f8a9441e7b75a82434' 
  AND token = 'or49mWTrj1ZHaZd313bHQmNMywmryp3iiCQRi1n+GIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}