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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74848262fb2c0d4a54f9a4e1cdb2530d3d758f9840b3b9e7c0dc494b401be429' 
  AND token = 'JdtcxI16qvoqW0Fp0Lt5ncbv+hlOfGZCkG36nLN+8vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}