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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd83c0ec31d66030d5434d3d0754018c4cf22fb3d7d5ff6a55dd496ebcf4c1647' 
  AND token = 'pzeP4npIAOfgQUKeM/IEX4huJno/DtgXzs6XyA0ZdeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}