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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c07748fb20937428041200b69433daa0c7dccdb10d8e08df816785e26d0a22' 
  AND token = 'R8D5YDBzwEnrKCS2u6430+Z/pnv5QTh5eyMlrhMSCiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}