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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b577270038ee20669042623f36f91047f3e5bbc10332acd625f278a84a8c808' 
  AND token = 'k5D7gUzm6kbPGdKh4PoFepC0mdNT0jFGPJwDLXEGRNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}