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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28f2736debbc24d3fb17de78a68aa92adb51053b5d104aaba27325ca3fc68c4' 
  AND token = '6cJT8IIn8Wu6te1KFUrJV3XGZMoOHv7WhJezpgAH/Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}