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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdfa5562b0cf64687db3141a81fe68c1b6d019bc554f1e48ce39d98684937b2' 
  AND token = 'Q2byTg/dG7o6HHgdTK0lOgUQUfyvZNqsYq1o0oFwyV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}