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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea21154f96420b92f71995546e672ec07d7fc79ae3bc178cc73f5b08d968dcb' 
  AND token = 'E+OkdP7IlL+d+vWQwlUFjim7p0Oy0jmySxUlhG+Jc7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}