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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ae98b857eb15eec17ab03214ed43035f47f1743dbc7ddca94a5d61e160c55c' 
  AND token = 'hCoMSUl6QcsdLmWtc7AY+JXxbsY3Edy2bhIKPRMg7eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}