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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6270729ecb865f1936a99087738f83be0dfcee1f02b33ddd24849e469c15756' 
  AND token = '0Ejd6u+jJQjyI7jICBSAbhWk5DA+0h2grZkxWbxwyCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}