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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ad754fec31d4dc27690e9cb1bb913745bbd8c7a6a82388928d9498474c92bc' 
  AND token = '35bZzOtIwrpik5yH7l/rErt7a1+wO8t12iYFOu0UYTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}