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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7ec02a8176329d90fccb4534441a381c2bbcdaefc4f07538d059bdbac1ee2f' 
  AND token = 'EWnaulzUL3LAex4L8D7+6JnO9T05i2Bt/vu6ZiBc15k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}