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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acbd47efe8dcd5abe7343abca47c90dd99a8221a9d0a81e9035445b928d91c0' 
  AND token = '24u5DfnPFPLsk3cCeUYrg749YocGwlVMOeamPScYJX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}