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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5a4f93a24c41e866522a7cd3b5987bcef322d0cbd935be20f3d9320a309333' 
  AND token = 'EJ4hWtGOj3jrD/9405vxi4hrRvHvAxy7LpQ/4qcnz8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}