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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f320f7bd5aecd76ced5792ebd042b4480f19c37fef0b2c5ea727a59a3ffeb10' 
  AND token = 'ievpV5bJ+4DtRq3tdL0vPvTatw6VeeBmI3ylLXV9GQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}