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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb24eb1e12e3a11bf2ec8a799a35813a008e0b05d0d9c57901c760198d73cbbb' 
  AND token = 'dR3AwBMLmnK7/S8+0qq8UPe+B/OVyrgySeCLs41QNMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}