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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cac78161cef5557a6ccefe4a310e37fff78b335ad50c88b910443561716dee' 
  AND token = '+4KsMs9HrU9F0/ZAiGR1dhlCyZkIo8k6zAY+jXrf6Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}