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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fd3781568aa36e857b39f11a5770ab15cc8f8a479d2a7bdbb221b3643f8a19' 
  AND token = 'jvuiT6beHnlypW4JxG8980yfIboH7r1FIIoE+DXzbK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}