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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ddc1e5ffb651038fb74319899206336b156b167fa0d8f419a04f25c6f61f73' 
  AND token = 'eymw6VGPF5caNOdSWfNwitGgPRlz/s5+OhsdAsDFqqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}