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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3891eef8155d7c9dbd11090a2cad96a873cae5b22f93edfa5ed4f4823eee103d' 
  AND token = '4T2Te2C3je5S1PZwP/xRp+aiHYpFUlsEJz9dTvNFE4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}