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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe969aee4045c6f06cdb03684dea95256ef3a4ad2819798c38a7e72e335d0339' 
  AND token = 'FQClWTB6qepFo1v2k3/cVScxHMwYHGkC719rQmxj6Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}