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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c23be230d4959a5c7c8108b14819af586b1a2b5028f517f40b17a108da752512' 
  AND token = 'SQxbhNwwKaKOgEB1MSCsgeSF22cnkp4+lbs0ZNZAiJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}