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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07c1d0150e6f8dcd4081f16663f5c21027cbac2262c68559da7a0f4851f2352f' 
  AND token = '47y4ZWEYhkCwunulZeX5SLzAmQTnRtU8+yOfB5NgfBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}