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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c650bb76f4ea753030795a9280a9f77c3fca0f8f14b74232d1ec75f84e66560' 
  AND token = 'swPcuDA1cx76KwAUK/CQWRP4Fu/abt5flJZMgbyuiXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}