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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8f8dea21b2e6fc3c0b09581aee5398d4fe2c2eca8a07d63965cb3a944bb470' 
  AND token = 'ukFYaF20wgkfb2nxw3YrEQH9XYjn4bsnFywdR+wNa2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}