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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9cb2243e77e3903b81e5c359bd450d3f7d69c52918fa09872ae0eb01ea34ea' 
  AND token = 'HJT3LtQ8+zqvSzg5dQ4rIkx1TWab0podm0iiSDh4PNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}