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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ddc706ab8ed86c866664938a2c89738be0a298c7383baa9eb1e746be9c6cfd' 
  AND token = 'wLFVF4X2Vftvxg8QBqcdbx7cAxKR2OwLGeBIsb5uQUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}