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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fbd3c6c054428cd10d359e17fb47631ef4f0a464a83fa912a3ce5c65d8fda27' 
  AND token = 'Rq2Dx+E3BEmmiRldhxxXzBpcSpST5gI+tVhTXvTGcKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}