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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d5a9fe3a7b7fa733773a59ca02f68e9d99cebc192af9ca899a20b42e55756d' 
  AND token = 'Egzf0XE4h3QMbb3AL3//Ka7zSb5AacK32bBLNNObVwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}