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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f578f278e48bec7e35eb319cec39349aedcc7e7dd614c116752df468bc8161eb' 
  AND token = 'onx1lQ1AJX4wv12q8l0gyKMB2tSC0pm4hnLSS69sTow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}