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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381eec6997c8cd05a2603d52b5a720c6876dd413288cbb5fa4f0302ec21c6058' 
  AND token = 'y/Nj7HMQWCzhkjs1S1UyWjf7VMDghJrbnIgY16kmp8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}