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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c935a033e8c29b0ce2e5a6c3269fec4b2913b1cac4c8bc4675c93c137adab590' 
  AND token = '6xYzT2SPKFyvL6QzEc0xBrsM0Ch5Ti4rHAAh9R4Pudc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}