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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e3d9f7a0cb2a65c22e4f4d81037333eb403d6d3b5374fa58f94553e5dc904a' 
  AND token = '3uqO4psPOEfspmTo+YvOtwM/3Hcuhl/aWG6Nnb3RuyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}