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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd21a9b80cf826b36e8de1b4f3339c6a529072e26ceb4fec61e4c8c0e663cb7e' 
  AND token = '5lZdJpRRm7llh38yMr2TeuDAzCPpielXtedMB7HoZlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}