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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adfc7586d1da0780bf6d0d38684e8d8beb835c057ea881e6d0890c206946cbb4' 
  AND token = 'Dtwp6sAcmEDHQljTd6sRbYRTe6bsw00lBYZQimqglvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}