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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375c7887068f932f1f94955044b9fb21ad6511408ffb7820bc47389954c5762d' 
  AND token = 'R4DN1hjGi779UWRXW8zFTY5TKx9LqTLuL96r2sP0Dqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}