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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758474ef8f6b11759a0b421f6c2dde2eef2ad51bb88fe19ffe4ee65d5d6483f7' 
  AND token = '7aXHpDJuwHVIwtuqASnLE/u/EX7FCLxVVfPDsmY+Oio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}